Noni AS CANCER DRUG

The use of noni for cancer treatment in recent years more and more popular as more research on the benefits of noni for cancer.
University of Hawaii research team led by Annie Hirazumi found that noni juice enhance the immune system works (mainly macrophages and lymphocytes) mice induced with Lewis lung cancer cells, thus able to survive 50 days more. Whereas mice not given noni only able to survive between 9-12 days. Annie is also observed that noni juice is useful for treating sarcoma.

Louisiana State University team, the U.S., led by Conrad A. Hornick, Ph.D. found that noni juice in the levels of 10% can stop the formation of blood vessels (anti-angiogenesis) in breast cancer cells and damage the blood vessels that cancer already exists, so the cancer cells die. 

Maria Gabriela was Manuele and his colleagues succeeded in proving that scopoletin can activate lymphocytes to eradicate cancer cells as well as lymphoma. 

Not to be outdone by his colleagues, Dr. Rangadhar Satapathy, MD stated that the noni plant has 150 Neutraceutical (medicinal nutrients), five of which are anticancer agents: 

(1) Polysaccharides are abundant in Morinda prevent the attachment of cells damaged / mutated into other cells, thus preventing the occurrence of metastases. 

(2) damnacanthal, similar anthraquinon, inhibits the growth of malignant cells. Alizarin, another anthraquinon, stopping blood flow to tumor tissue, thus stopping its development. 

(3) Epigollocatechin gallate (EGCG). Polyphenolic antioxidant flavonoid that is widely available in this noni prevent mutation of cells and induce apoptosis (suicide) in the abnormal cells. 

(4) terpenoids in noni preventing malignant cell division and induce apoptosis. One terpenoidnya, limonene, proven effective against breast cancer, liver cancer, lung cancer, and leukemia. Other terpenoids, beta-carotene, helps stimulate the thymus gland to produce more T lymphocytes, cells that can directly destroy cancer cells. Moderate acid type triterpenoid ursolat also can prevent the growth of abnormal cells (cancer) as well as send existing abnormal cells to commit suicide (apoptosis). 

(5) According to the research of Dr.. Heinicke, proxeronine very much present in Noni. In the intestine is converted to xeronine proxeronine. Xeronine is also produced in limited quantities this body is required to activate proteins in the cell before it is used throughout the chemical process of the body. Xeronine also improve the structure and function to normalize the body's cells are damaged. Because, basically, every cell contains a protein, then the adequacy of xeronine can fix any kind of abnormal cells. From here obtained an explanation, why xeronine different effects on each person, but generally showed improvement according to each disease. 

But behind the impressive benefits of noni so there is one thing that is often an obstacle in taking noni, that smells bad. Aroma is quite pungent, caused by acid and capric acid kaproat there is lots of ripe noni fruit. The means used to reduce this scent is a blend of honey or brown sugar into noni juice, then stored in glass or glass bottles for 2-4 days. 

In this fermentation process kaproat acid and capric acid will decompose so that the smell is reduced, unfortunately not yet obtained clear whether this affects the usefulness of fermentation process or not. According to the testimony of its users, noni fruit is not ripe old (not many kaproat acid and capric acid) was less potent than noni fruit is completely ripe.

General characteristics of Noni

Tree

Noni is not that big tree, in height from 4-6 m. trunk twisted, branchy stiff, coarse, and has its roots embedded in the riding. Bark grayish brown or yellowish brown kuniangan, parted in the shallow, not hairy, bersegai four subsidiaries. Editorial suklalu evergreen. Noni is easy to split wood after drying. Can be used to support pepper plants.

Leaf 

Thick, shiny leaves. Noni leaf is face to face. Leaf size were large, thick, and a single. The shape is oblong-lanceolate, 15-50 x 5-17 cm. leaf edges flat, short pointed tip. The base of the wedge-shaped leaves. Veins pinnate leaves. Hiaju color glossy, hairless. The base of the leaves short, measuring 0.5 to 2.5 cm. fulcrum leaf size varies, the width is triangular. Noni leaves can be eaten as a vegetable. High nutritional value because it contains vitamin A.
 

Interest

Noni rounded hump-type inflorescence, 1-4 cm handle. Flowers grow in axillary leaves the fulcrum of dealing with leaves that grow normally. The flowers are androgynous. Petals white, funnel-shaped, 1.5 cm in length can be achieved. Stamens sticking in the mouth of the crown. Berputing two anthers. Flower petal-shaped blooms of the bunch. The flowers are white, fragrant.

Fruit

Petals oval to grow into a round of chicken eggs and some have a diameter of 7.5 to 10 cm. The fruit surface as divided into polygonal cells (in terms of many) who spotted and warty. At first the fruit is green, a yellowish white before cooking. Once cooked, the color is transparent white and tender. The pulp is composed of stone fruit pyramid-shaped, red-brown. Once soft, noni fruit contains a lot of water that smells like rotten cheese. The odor arising from mixing between the acid and acid kaprik kaproat (lipid or fatty compounds that volatile molecular clusters, a nature such as essential oils) that smells rancid and caprylic acid that tastes bad. Presumably both of these compounds are active as an antibiotic.

The content of Noni

Nutrients: whole noni fruit is full of nutritious food. Nutrients the body needs, such as protein, viamin, and essential minerals, available in sufficient quantities in fruit and noni leaf. Selenium, a mineral found in Noni is a powerful antioxidant. Various types of compounds contained in Noni: xeronine, plant sterois, alizarin, lycine, sosium, caprylic acid, arginine, proxeronine, antra quinines, trace elemens, phenylalanine, magnesium, etc..

     Terpenoids. It helps in the process of organic synthesis and recovery of the body's cells.
     Bakteri.Zat anti-active substances contained in Noni juice can kill the bacteria that cause infections, such as Pseudomonas aeruginosa, Protens morganii, Staphylococcus aureus, Bacillus subtilis, and Escherichia coli. Anti-bacterial substance that can also control the bacterial pathogen (turn off) such as Salmonella montivideo, S. scotmuelleri, S. typhi, and Shigella dusenteriae, S. flexnerii, S. pradysenteriae, and Staphylococcus aureus.

     Scolopetin. Scolopetin compounds are very effective as a element of anti-inflammatory and anti-allergic.

     Anti-cancer substances. Anti-cancer substances found in Noni most effective against the abnormal cells.

     Xeronine and proxeronine. One of the important alkaloids within noni terdapt is xeronine. Noni fruit contains very little xeronine, but contains a lot of stuff of the (precursor) xeronine alias proxeronine in large numbers. Proxeronine is a kind of nucleic acids such as colloid-colloid others. Xeronine absorbed by the body's cells to enable protein-protein which is inactive, set the structure and shape of the active cell.